Kariyat capsule
แคปซูลฟ้าทะลายโจร
แคปซูลฟ้าทะลายโจร,  Kariyat capsule, 100 capsules,500 mg/ capsules
 
 
FAH-TALAI-JONE, kariyat capsule
Potential Benefits of Andrographis
Previous studies have found that andrographis may have benefits for other viral infections. A 2004 study that involved 133 children with the common cold compared a preparation of echinacea (Echinacea purpurea, Asteraceae) in combination with standard conventional medical treatment, a preparation containing andrographis in combination with standard treatment, and standard treatment only. All three groups experienced improvements in upper respiratory symptoms, but the children who received the preparation containing andrographis recovered from symptoms significantly faster than children in the two other groups.9
A 2017 systematic review that included 33 randomized, controlled trials (N = 7,175) suggested that andrographis may have benefits for acute respiratory tract infections (ARTIs). Andrographis improved cough and sore throat compared to placebo and significantly improved overall symptoms of ARTIs compared to placebo and other herbal treatments. The meta-analysis of 12 clinical studies comparing andrographis to usual care (conventional treatment with analgesics, antibiotics, anti-inflammatories, antivirals, corticosteroids, or steroids) indicated a statistically significant reduction in the duration of sore throat and sick leave, but not cough. No major adverse events (AEs) were reported, while minor AEs were mostly gastrointestinal. However, the overall methodological quality of included studies was rated “poor.”10
Andrographis is the main ingredient of the multi-herb formula Nilavembu Kudineer, which is used in Siddha medicine of India and also includes nutgrass (Cyperus rotundus, Cyperaceae), threadstem carpetweed (Mollugo cerviana, Molluginaceae), black pepper (Piper nigrum, Piperaceae), Indian sandalwood (Santalum album, Santalaceae), snake gourd (Trichosanthes cucumerina, Cucurbitaceae), vetiver (Vetiveria zizanioides, Poaceae), and ginger (Zingiber officinale, Zingiberaceae). Traditionally, these plants have been used to treat arthralgia (joint pain), arthritis, fever, gastric ulcers, general debility, inflammation, and jaundice. In a 2018 study, an ethanolic extract of Nilavembu Kudineer provided protection against dengue virus (a flavivirus) and chikungunya virus (an alphavirus) during active infection and helped prevent viral infection in cell cultures that were pre-treated with the formula.11
In a 2018 study, arthritic rats were given andrographolide combined with the conventional drug methotrexate, which can be hepatotoxic. Another group of rats received methotrexate only and another group received andrographolide only. Andrographolide improved the anti-arthritic effect of methotrexate. The combined therapy additively reduced inflammatory symptoms in the rats and significantly alleviated hepatocellular injury induced by methotrexate, according to the authors.12
In a 2019 study, pre-treatment with andrographolide sulfonate (AS), a water-soluble form of andrographolide, significantly attenuated lung injury and infiltration of inflammatory cells in mice infected with the bacterium Klebsiella pneumoniae, which is a major cause of respiratory infections. Mice treated with AS alone died after six days of infection, while a control group that received only the antibiotic imipenem had a survival rate of 33.3% after 15 days of infection. However, AS combined with imipenem resulted in 100% survival after 15 days of infection. This suggests that AS could synergistically improve the efficacy of imipenem